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Tuesday, March 1, 2011

RESEARCHERS SEE NO PPI ATTENUATION OF CLOPIDOGREL ANTIPLATELET EFFECTS IN FRENCH MI REGISTRY ANALYSIS

HeartWire (1/26, Stiles) reported that "no significant sign of excess cardiovascular events, including death, MI, or stroke in-hospital or at one year, were seen in patients who received proton-pump inhibitors (PPIs), especially omeprazole, along with clopidogrel in a French MI registry." This "was seen regardless of whether patients carried a gene variant known to interfere with clopidogrel's antiplatelet action, according to investigators in a report published online January 24, 2010 in Circulation."

POSTED BY STEVEN ALMANY, MD

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